Olivier Chassande

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Patents:

1- McAllister, T., and L'Heureux, N. Tissue engineered cellular sheets, and methods of making same. USPTO Patent No. 8,076,137 (December 13, 2011).

2- McAllister, T., and L'Heureux, N. Bioreactor for the manufacture of tissue engineered blood vessels. USPTO Patent No. 7,744,526 (June 29, 2010).

3- McAllister, T., and L'Heureux, N. Tissue engineered cellular sheets, methods of making and use thereof. USPTO Patent No. 7,504,258 (March 17, 2009).

4- McAllister, T., and L'Heureux, N. Method of culturing cells to produce a tissue sheet. USPTO Patent No. 7,166,464 (January 23, 2007).

5- McAllister, T., and L'Heureux, N. Tissue engineered blood vessels and apparatus for their manufacture. USPTO Patent No. 7,112,218 (September 26, 2006).

6- McAllister, T., and L'Heureux, N. Tissue engineered blood vessels and methods and apparatus for their manufacture. USPTO Patent No. 6,503,273 (January 7, 2003).

7- L'Heureux, N., Auger, F.A., and Germain, L. Production of a contractile smooth muscle. USPTO Patent No. 5,618,718 (April 8, 1997).

✔ Animal experimention

✔ Mouse genetics models

✔ In vitro/in vivo bioluminescence

✔ In vitro/in vivo fluorescence

✔ Hydrogels

✔ Hydrogels bioactifs

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+(33) 05 57 57 17 54

Olivier.chassande@inserm.fr

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BIOMAT

ISACB

Dr. Olivier Chassande

CR1 (CNRS), HDR

Is a recognized researcher at CNRS, he specializes in tissue engineering and biomaterials, with a primary focus on the development and characterization of biomimetic hydrogels used as 3D scaffolds for cell culture, providing a conducive environment for cell differentiation and maturation. His work centers on cell–matrix interactions and the modulation of tissue responses to biomaterial implantation—such as inflammation, vascularization, and fibrosis—with the goal of improving implant biocompatibility. His innovative approach includes the use of advanced imaging techniques such as bioluminescence and tomo-fluorescence to monitor, in real time, the integration and fate of implants within living tissues. In collaboration with leading laboratories, he contributes to the development of advanced biomedical solutions for tissue regeneration and implantable medical devices. His expertise places his research at the forefront of regenerative medicine innovation, with promising applications for treating bone, cartilage, and vascular pathologies. Additionally, he plays a key role in technology transfer and the commercialization of scientific innovations, helping to foster the emergence of new ventures in the field of biomaterials. Through interdisciplinary collaboration, he actively bridges fundamental research with clinical applications.

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